Nutritional rehabilitation: from pulmonary cachexia to sarcoPD.

E vidence is accumulating that disease burden in chronic obstructive pulmonary disease (COPD) is determined by not only pulmonary impairment but the fact that skeletal muscle pathology and cardiovascular disease also contribute to decreased physical performance and increased mortality. An integrated view of the decline in function of multiple organs as a disturbed homeostatic network resulting from smoking, suboptimal diet, inactivity and disease susceptibility has not yet been conceptualised in COPD management but could lead to a shift in clinical medicine and public health towards personalised lifestyle.